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How Amgen Makes its Money: Revenue Breakdown

A breakdown of Amgen (AMGN) financials. See how Amgen makes money from Enbrel (autoimmune), Prolia (bone health), XGEVA (bone metastases), and more using their 2024 annual report.

Amgen at a Glance
Company
Amgen
Ticker
AMGN
Sector
Biotechnology
Market Cap
$160B
Last Updated
March 18, 2026
Source
SEC Filings (10-K)

How Does Amgen Make its Money?

Amgen is one of the world’s largest biotechnology companies, focused on discovering, developing, and delivering innovative medicines. The company’s portfolio includes blockbuster drugs targeting oncology, cardiovascular disease, bone health, and inflammation. Amgen significantly expanded its drug portfolio in 2023 through its $28 billion acquisition of Horizon Therapeutics, adding rare disease therapies to its lineup. The company continues to invest heavily in its biosimilar pipeline and next-generation obesity drug MariTide.

Amgen (AMGN) Business Model

Amgen operates in the biotechnology sector. Below is a summary of Amgen’s revenue streams, how the company generates income, and the key financial metrics from its most recent annual report. This breakdown uses data from Amgen’s 2024 fiscal year filings with the SEC.

Amgen Competitors

Amgen’s key competitors and comparable public companies in the biotechnology sector include Eli Lilly, Novo Nordisk, Gilead Sciences, and Pfizer. Each of these companies competes for market share, investor attention, and revenue in overlapping segments. See how Amgen stacks up by comparing their revenue breakdown, margins, and growth metrics.

Amgen Competitors

Amgen’s key competitors and comparable public companies in the biotechnology sector include Eli Lilly, Novo Nordisk, Gilead Sciences, and Pfizer. Each of these companies competes for market share, investor attention, and revenue in overlapping segments. See how Amgen stacks up by comparing their revenue breakdown, margins, and growth metrics.

Amgen Competitors

Amgen’s key competitors and comparable public companies in the biotechnology sector include Eli Lilly, Novo Nordisk, Gilead Sciences, and Pfizer. Each of these companies competes for market share, investor attention, and revenue in overlapping segments. See how Amgen stacks up by comparing their revenue breakdown, margins, and growth metrics.

Amgen Competitors

Amgen’s key competitors and comparable public companies in the biotechnology sector include Eli Lilly, Novo Nordisk, Gilead Sciences, and Pfizer. Each of these companies competes for market share, investor attention, and revenue in overlapping segments. See how Amgen stacks up by comparing their revenue breakdown, margins, and growth metrics.

Amgen Competitors

Amgen’s key competitors and comparable public companies in the biotechnology sector include Eli Lilly, Novo Nordisk, Gilead Sciences, and Pfizer. Each of these companies competes for market share, investor attention, and revenue in overlapping segments. See how Amgen stacks up by comparing their revenue breakdown, margins, and growth metrics.

Amgen Competitors

Amgen’s key competitors and comparable public companies in the biotechnology sector include Eli Lilly, Novo Nordisk, Gilead Sciences, and Pfizer. Each of these companies competes for market share, investor attention, and revenue in overlapping segments. See how Amgen stacks up by comparing their revenue breakdown, margins, and growth metrics.

Amgen Competitors

Amgen’s key competitors and comparable public companies in the biotechnology sector include Eli Lilly, Novo Nordisk, Gilead Sciences, and Pfizer. Each of these companies competes for market share, investor attention, and revenue in overlapping segments. See how Amgen stacks up by comparing their revenue breakdown, margins, and growth metrics.

Revenue Breakdown

Segment 2024 2023 YoY Growth
Enbrel (autoimmune) $3,200 $3,700 -13.5%
Prolia (bone health) $4,200 $3,900 +7.7%
XGEVA (bone metastases) $2,200 $2,100 +4.8%
Repatha (cholesterol) $2,600 $1,900 +36.8%
EVENITY (osteoporosis) $1,500 $1,100 +36.4%
TEZSPIRE (asthma) $1,300 $800 +62.5%
Horizon portfolio & Other Products $18,400 $15,700 +17.2%
Total Revenue $33,400 $28,200 +18.4%

Enbrel (autoimmune) — 10% of Revenue

Prolia (bone health) — 13% of Revenue

XGEVA (bone metastases) — 7% of Revenue

Repatha (cholesterol) — 8% of Revenue

EVENITY (osteoporosis) — 4% of Revenue

TEZSPIRE (asthma) — 4% of Revenue

Horizon portfolio & Other Products — 55% of Revenue

Income Statement Overview

Metric 2024 2023
Total Revenue $33,400 $28,200
Cost of Revenue $11,800 $8,300
Gross Profit $21,600 $19,900
Operating Expenses $14,800 $14,600
Operating Income $6,800 $5,300
Net Income $5,700 $4,800

All values in millions USD unless otherwise stated.

Key Financial Metrics

  • Gross Margin: 64.7%
  • Operating Margin: 20.4%
  • Revenue Growth: 18.4%

Is Amgen Profitable?

Yes, Amgen is profitable. The company reported net income of $5,700 on total revenue of $33,400. With an operating margin of 20.4%, Amgen demonstrates solid profitability for the biotechnology sector. The gross margin of 64.7% reflects Amgen’s pricing power and cost structure.

What to Watch

  1. Clinical trial results for MariTide, Amgen’s GLP-1 obesity drug candidate
  2. Integration of Horizon Therapeutics assets and revenue trajectory of TEPEZZA
  3. Enbrel revenue decline as biosimilar competition intensifies
  4. Growth of newer drugs like TEZSPIRE, Repatha, and EVENITY offsetting mature product declines

Amgen (AMGN) Financial Summary

Amgen (AMGN) is a biotechnology company that generated $33,400 in total revenue in fiscal year 2024. Revenue grew 18.4% year-over-year. The company earned $5,700 in net income, making it profitable. For a deeper look at Amgen’s revenue breakdown, business segments, and financial performance, review the detailed analysis above.

Frequently Asked Questions

How does Amgen make money?

A breakdown of Amgen (AMGN) financials. See how Amgen makes money from Enbrel (autoimmune), Prolia (bone health), XGEVA (bone metastases), and more using their 2024 annual report.

What is Amgen's stock ticker symbol?

Amgen trades on the stock market under the ticker symbol AMGN.

What is Amgen's market cap?

Amgen's market capitalization is approximately $160B.

What sector does Amgen operate in?

Amgen operates in the Biotechnology sector.

Is Amgen publicly traded?

Yes, Amgen is a publicly traded company listed under the ticker AMGN with a market capitalization of approximately $160B.